What are the risks of taking compunded GLP-1s?

Unapproved versions of GLP-1 (glucagon-like peptide-1 (GLP-1) receptor agonists) medications, specifically including semaglutide and tirzepatide can be extremely hazardous. Unapproved medications do not go through the FDA’s review process for safety, effectiveness and quality. Injectable GLP-1 medications require refrigeration. There have been many reports of compounded GLP-1 meds arriving warm and not containing adequate ice packs to maintain the drugs at proper required storage temperatures. The FDA warns patients against using injectable GLP-1 medications that are warm upon arrival or do not contain proper refrigeration. Improper refrigeration can affect a medications quality. Some fraudulent compounded semaglutide and tirzepatide sold in America may provide fraudulent information on the product label. In certain instances, the compounding pharmacies marked on the drug label are nonexistent.